Then you're going to have a hard time in the post Node.js era. You also probably want to avoid looking at what many popular desktop apps use behind the scenes :)
I avoid any desktop app that uses electron or similar. Electron is still a hog, and most things written in electron have alternatives. I don't use the slack desktop app for this reason, as an example.
Minus the browser. Each Electron app isn’t just the running web app but also the browser instance too. Where as a web app running in a browser wouldn’t consume its own browser instance.
That browser instance alone can make quite a noticeable difference.